Analysis of the long-term results of surgical treatment of patients with multifocal atherosclerosis in different age groups

Abstract

Purpose. The study of long-term results staged reconstructive operations on coronary and non-coronary arterial basins in patients with multifocal atherosclerosis (MFA) in different age groups.
Material and methods. It was included 764 consecutive patients (655 men and 109 women) aged 39 to 84 years with MFA, who underwent isolated coronary artery bypass grafting (CABG) or CABG in combination with simultaneous or staged surgical interventions in the non-coronary vascular beds. The treatment procedure was defined by the heart team with the inclusion of cardiovascular surgeons, cardiologists and anesthesiologists. Depending on the age of patients formed 4 groups: Group 1 – patients up to 60 years (n=338), 2 group – 60–64 years (n=185), 3 group – 65–69 years (n=137) and group 4 – patients 70 years and older (n=104).
Results. Long-term results after reconstructive operations on various vascular regions analyzed in 85.3% of patients, and the median follow-up was 47,8±21,7 months. Total mortality, mortality from cardiovascular disease and other causes increased with age, but not observed statistical significance between the groups. The groups also did not differ between themselves and the number of recurrent angina (p=0,217), myocardial infarction (p=0,311) and stroke \ TIA (p=0,161).
Conclusion. The use of differentiated surgical approach proved safe and effective in patients with MFA regardless of age, which is confirmed by long-term results obtained are comparable with findings in younger patients.