In-hospital outcomes of pharmacoinvasive approach in patients with acute myocardial infarction with ST-segment elevation

Abstract

Aim. The evaluation of in-hospital outcomes of pharmacoinvasive approach in real practice.
Material and Methods. 90 patients were included in the present study. They were admitted to hospital from February to October 2010 with ST elevation myocardial infarction within 6 hours from the onset of symptoms. All patients received prehospital thrombolytic therapy (TLT). Patients were divided into 2 groups according to TLT results. 38 patients achieved electrocardiography (ECG) confirmed success of TLT within 90 min and formed the facilitated percutaneous coronary intervention (PCI) group. Another 52 patients had not ECG signs of reperfusion after 90 min from the beginning of TLT and they were included to the rescue PCI group. In all patients of both groups PCI was completed by stent implantation.
Results. Generally 52 culprit lesions in the rescue PCI group were treated by 71 stent implantation (1.37±0.63 per patient) and in the facilitated PCI group there were 56 stent implantations (1.47±0.60 per patient) in 38 culprit lesions. PCI with stent implantation has been successfully completed in all cases, so an immediate success in both groups achieved 100%. One day after initial PCI a repeat successful PCI with new stent implantation was performed in 1 patient of the facilitated PCI group.