The influence of chemokines on the formation of atherosclerotic lesions by regulating the function of leukocytes

Authors

  • I. V. Sergienko FSU Russian Cardiological Research and Production Complex of the Ministry of Health of the Russian Federation
  • D. N. Nozadze FSBI Russian Cardiology Research and Production Complex of the Ministry of Health and Social Development of the Russian Federation
  • E. I. Kaznacheeva FSBI Russian Cardiology Research and Production Complex of the Ministry of Health and Social Development of the Russian Federation

Keywords:

MCP-1, fraktalkin, interleukin 8, macrophage migration inhibitory factor, heteromeric complexes of chemokines

Abstract

This paper describes the processes that regulate the function of leukocytes in the formation of atherosclerotic plaque. In
particular, it illustrates the role of MCP-1, interleukin 8, fraktalkin, macrophage migration inhibitory factor, arterial
colony stimulating factor-1. The authors describe the mechanisms that are included in the early and advanced stages
of atherosclerotic process and different role of the various subclasses of monocytes, which are known to be differently
involved in the formation of atherosclerotic plaque

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Published

2012-09-30

How to Cite

Sergienko I. V., Nozadze D. N., Kaznacheeva E. I. The influence of chemokines on the formation of atherosclerotic lesions by regulating the function of leukocytes // The Journal of Atherosclerosis and Dyslipidemias. 2012. VOL. № 3 (8). PP. 37–47.

Issue

No. 3 (8) (2012)

Section

Review

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