Therapy with PCSK9 (alirocumab) inhibitors in patients with ischemic stroke in the Komi Republic

Abstract

This article examines the place of cardiovascular diseases (CVD) in the structure of mortality on the example of three countries of the South Caucasus (Armenia, Azerbaijan, and Georgia) and Turkey. The populations of these countries have similar lifestyles and traditions, while the health care system and the socio-economic system accommodate their own characteristics. In all 4 countries, the top two causes of death among the working-age population are coronary heart disease (CHD) and cerebral stroke. The contribution of CHD to mortality ranges from 32% in Georgia to 42% in Azerbaijan. The contribution of cerebral stroke to mortality ranges from 10% in Armenia to 24% in Georgia. Every second man and up to 7% of women smoke. The prevalence of obesity and tobacco smoking among men in 4 countries is comparable. At the same time, in Georgia and Armenia, men drink alcohol 2-3 times more than in Turkey and Azerbaijan. The highest incidence of obesity was found among women in Turkey, at 39.2%. In the countries of the South Caucasus, a high incidence of obesity was found among women and, on average, amounted to 23.5%. The countries of the South Caucasus face a major challenge in reducing the incidence and secondary prevention of CVD among the adult population.