Возможности ультразвукового  метода исследования эпикардиальной  жировой ткани у пациентов  с ишемической болезнью сердца  при различной тяжести поражения  коронарных артерий

E. A. Polyakova; S. E. Nifontov; M. I. Butomo; O. A.  Berkovich; E. I. Baranova

doi:10.34687/2219-8202.JAD.2019.04.0006

Authors

E. A. Polyakova First Saint-Petersburg State Pavlov Medical University, Federal Almazov North-West Medical Research Centre
S. E. Nifontov First Saint-Petersburg State Pavlov Medical University
M. I. Butomo First Saint-Petersburg State Pavlov Medical University
O. A. Berkovich First Saint-Petersburg State Pavlov Medical University, Federal Almazov North-West Medical Research Centre
E. I. Baranova First Saint-Petersburg State Pavlov Medical University, Federal Almazov North-West Medical Research Centre

DOI:

https://doi.org/10.34687/2219-8202.JAD.2019.04.0006

Keywords:

coronary artery atherosclerosis, coronary artery disease, epicardial adipose tissue, echocardiography

Abstract

Objective. To assess the diagnostic capabilities of the ultrasound method for estimation of the epicardial adipose tissue (EAT) and evaluate the effect of the thickness of epicardial fat on the extent of coronary atherosclerosis in coronary artery disease (CAD) patients.
Methods. 461 people (mean age 52 years, Q1 = 44; Q3 = 56) were examined: 182 patients with CAD (132
men and 50 women), 279 – without CAD (60 men and 219 women). Coronary angiography, heart computed tomography (CT), echocardiography (ECHO-KG) were estimate. Measurements of height, weight, waist circumference were carried out, body mass indices were calculated (BMI, kg/m2). Statistical data analysis was performed using the statistical software package SPSS, version 17.0 (SPSS Inc., USA).
Results. In CAD patients the volume of EAT (according to CT) was significantly higher than in patients without CAD. According to multiple linear regression analysis, it was found that in patients with CAD, an increase in age of 1 year is associated with an increase in the volume of EAT by 1.4 cm3, and also, in patients with CAD, the volume of EAT is on average 56.7 cm3
more than in patients without coronary atherosclerosis. The thickness of EAT in the atrioventricular sulcus (according to the ECHO-KG) most closely corresponds to the volume of EAT (according to cardiac CT). The relationship between the number
of coronary arteries affected by atherosclerosis and the values of the studied parameters characterizing the of EAT was not revealed.
Conclusions. The thickness of EAT in the atrioventricular sulcus, measured by the ECHO-KG, is most correlated with the volume of EAT, assessed by CT of the heart. The volume of EAT in patients with coronary artery disease, as measured by CT of the heart, is greater than that of those examined without coronary artery disease. The volume of EAT in patients with CAD, as measured by CT of the heart, increases with age. The number of coronary arteries affected by atherosclerosis in CAD patients does not depend on the thickness and volume of EAT.