(An update on the relationships between rheumatoid arthritis and atherosclerosis

Abstract

Serdechno-sosudistyye sobytiya – samaya vazhnaya prichina smertnosti i zabolevayemosti u patsiyentov s revmatoidnym artritom. Vne traditsionnykh serdechno-sosudistykh faktorov riska khronicheskoye sistemnoye vospaleniye yavlyayetsya reshayushchim faktorom v razvitii ateroskleroza i yego progressii ot endotelial'noy disfunktsii do razryva ateroskleroticheskoy blyashki i tromboza. Mnogiye issledovaniya pokazali, chto ateroskleroz ne yavlyayetsya passivnym nakopleniyem lipidov v stenkakh sosudov, a predstavlyayet soboy aktivnoye vospaleniye sosudov. Vospalitel'nyye faktory, takiye kak makrofagi, monotsity i T-kletki igrayut vazhnuyu rol' v razvitii i revmatoidnogo artrita, i ateroskleroza. V etoy stat'ye analiziruyutsya vzaimosvyazi mezhdu revmatoidnym artritom i aterosklerozom. Ещё       volume_up 730 / 5000 Cardiovascular events are the most important cause of death and morbidity in patients with rheumatoid arthritis. Outside of traditional cardiovascular risk factors, chronic systemic inflammation is a critical factor in the development of atherosclerosis and its progression from endothelial dysfunction to atherosclerotic plaque rupture and thrombosis. Many studies have shown that atherosclerosis is not a passive accumulation of lipids in the walls of blood vessels, but is an active inflammation of the vessels. Inflammatory factors such as macrophages, monocytes and T cells play an important role in the development of both rheumatoid arthritis and atherosclerosis. This article analyzes the relationship between rheumatoid arthritis and atherosclerosis.