Сombination of thrombolytic therapy and percutaneous coronary interventions in treatment of ST elevation myocardial infarction

Authors

  • T. T. Sadykov Russian Cardiology Research Complex
  • A. N. Samko Russian Cardiology Research Complex
  • I. I. Staroverov Russian Cardiology Research Complex
  • E. M. Merkulov Russian Cardiology Research Complex
  • V. M. Mironov Russian Cardiology Research Complex

Keywords:

ST-segment elevation myocardial infarction (STEMI), hrombolytic therapy (TLT), percutaneous coronary intervention (PCI), reperfusion, prepared by PCI, life-saving PCI

Abstract

This study was done to evaluate the results of a combination of thrombolytic therapy (TLT) and percutaneous
coronary interventions (PCI) at the first day of the ST-elevation myocardial infarction (STEMI). We included 90
patients, which received prehospital TLT earlier 6 hours of development of chest pain and were referred to subsequent
PCI. Reperfusion after 90 min of TLT was successful in 51 patients, so PCI in these cases were facilitated. In another 31
patients we couldn’t find signs of reperfusion, so PCI in these cases were rescued. Inhospital outcomes were successful
in all cases, all patient were alive and discharged. Repeat PCI were successfully performed in 1 case at 7 day after
initial treatment. During follow-up to 12 month 5 patients (6%) died, 12 patients (13%) had repeat angina and they
had repeat revascularization procedures (11 PCI and 1 CABG). 73 patients (81%) till 12 months were event-free of
any complications.

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Published

2012-12-27

How to Cite

Sadykov T. T., Samko A. N., Staroverov I. I., Merkulov E. M., Mironov V. M. Сombination of thrombolytic therapy and percutaneous coronary interventions in treatment of ST elevation myocardial infarction // The Journal of Atherosclerosis and Dyslipidemias. 2012. VOL. № 4 (9). PP. 78–85.

Issue

Section

Original research paper

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