Risk assessment of clinical atherosclerosis complications by the estimation of common carotid and femoral arteries’ intima-media thickness

Authors

  • A. E. Filippov Saint-Petersburg State University, International medical center «SOGAZ»
  • A. G. Obrezan Saint-Petersburg State University, International medical center «SOGAZ»
  • B. V. Pomogaybo 413 military hospital
  • P. V. Bovtyushko Medico-military academy named after Kirov

Keywords:

atherosclerosis, arterial intima-media thickness, risk factors, low and moderate cardiovascular risk cohort, cardiovascular events

Abstract

The carotid and femoral arterials intima-media thickness (IMT) was investigated in an isolated sample of 207 men without clinical evidence of atherosclerosis (2414 observations). It was established that risk factors such as age, systolic blood pressure and blood serum cholesterol level, which are the main components of the SCORE model, have direct correlation with IMT (of medium strength (r=0,57, p<0,0001), which allows to explain the variance of IMT value no more than 33%. It was shown that the evaluation of the common carotid and femoral arteries of IMT in men with risk value of >1 % and<5 % according to the SCORE model may significantly improve sensitivity of the coronary risk evaluation. At the same time, a significant number of individuals free from cardiovascular events were put into a group of poor prognosis probably due to a high probability of false positive response.

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Published

2016-09-27

How to Cite

Filippov A. E., Obrezan A. G., Pomogaybo B. V., Bovtyushko P. V. Risk assessment of clinical atherosclerosis complications by the estimation of common carotid and femoral arteries’ intima-media thickness // The Journal of Atherosclerosis and Dyslipidemias. 2016. VOL. № 3 (24). PP. 39–46.

Issue

No. 3 (24) (2016)

Section

Original research paper

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