Age+related complications in patients with reconstructive aortic and low limb arteries surgery

Abstract

A total of 290 patients with peripheral arterial disease have undergone reconstructive aortic and low limb arteries interventions. According to age, patients were divided into three groups: I group (n = 91) included patients younger 50 years; II group (n = 95) – at the age of 50-59 year; III group (n = 104) included patients over 60 years old. The rate of yearly thrombotic events was higher in patients younger 50 years compare with patients older age groups. Systematic complications have observed in 72 patients (24,8 %). The rate of systematic complications has dramatically increased with age. We have not found any statistically differences between complication rates in young and old patients follow suprainguinal and infrainguinal interventions (5,9 % vs. 4,3 %, consequently). Systematic complications were more frequent after aorto-iliac reconstruction than infrainguinal in patients of II and III groups. The average rate in-hospital mortality was – 2.1 % (inhospital mortality of I, II and III group was 1,1 %, 2,1 % and 2,9 %, consequently). Long-term outcomes of 111 patients have been assessed (the median follow-up period was 48,3 months). Age-related 5-year survival rate for operated individuals in I, II and III group was 85,0±9,8 %, 78,1±14,6 % и 72,1±15,8 %, consequently. The leading reasons for death in each group were cerebral and coronary catastrophes. The primary 5-year patency rate in patients of I group was lower than in more elderly patients (61,9±14,4 % - for I group vs. 81,7±15,0 % and 92,1±11,0 % in patients of II and III group, consequently (p< 0,05)). A dominant reason for reocclusion in young patients within a period of 1-2 years follow surgery was intimal hyperplasia.