Сombination of thrombolytic therapy and percutaneous coronary interventions in treatment of ST elevation myocardial infarction
Keywords:
ST-segment elevation myocardial infarction (STEMI), hrombolytic therapy (TLT), percutaneous coronary intervention (PCI), reperfusion, prepared by PCI, life-saving PCIAbstract
This study was done to evaluate the results of a combination of thrombolytic therapy (TLT) and percutaneous
coronary interventions (PCI) at the first day of the ST-elevation myocardial infarction (STEMI). We included 90
patients, which received prehospital TLT earlier 6 hours of development of chest pain and were referred to subsequent
PCI. Reperfusion after 90 min of TLT was successful in 51 patients, so PCI in these cases were facilitated. In another 31
patients we couldn’t find signs of reperfusion, so PCI in these cases were rescued. Inhospital outcomes were successful
in all cases, all patient were alive and discharged. Repeat PCI were successfully performed in 1 case at 7 day after
initial treatment. During follow-up to 12 month 5 patients (6%) died, 12 patients (13%) had repeat angina and they
had repeat revascularization procedures (11 PCI and 1 CABG). 73 patients (81%) till 12 months were event-free of
any complications.