Statins in the treatment of chronic heart failure

Authors

  • O. M. Drapkina Clinic for Propedeutics of Internal Diseases, Gastroenterology and Hepatology. V.Kh. Vasilenko Moscow Medical Academy. I. M. Sechenova
  • O. N. Korneev The Internal diseases propedeutical clinic of I.M. Sechenov First Moscow State Medical University
  • L. O. Palatkina The Internal diseases propedeutical clinic of I.M. Sechenov First Moscow State Medical University
  • V. T. Ivashkin The Internal diseases propedeutical clinic of I.M. Sechenov First Moscow State Medical University

Keywords:

statins, cholesterol, chronic heart failure, pleiotropic effect of statins

Abstract

While there has been considerable progress in treatment of chronic heart failure, this pathology is still prognostically unfavorable disease. The Scientifics are not yet able to agree on whether to use statins in CHF. Data on the efficacy and safety are contradictory and require clarification, because patients with heart failure are systematically excluded from most large trials with statins. Given that the reduction of LDL is not the only mechanism for the positive effect of statins in patients with CHF, attaches great importance to pleiotropic effects of this class of drugs.

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Published

2012-03-28

How to Cite

Drapkina O. M., Korneev O. N., Palatkina L. O., Ivashkin V. T. Statins in the treatment of chronic heart failure // The Journal of Atherosclerosis and Dyslipidemias. 2012. VOL. № 1 (6). PP. 32–36.

Issue

No. 1 (6) (2012)

Section

Review