Junion junction in mechanisms action drugs in hypolipidemic and antithrombotic therapies. Review

Abstract

Studies of junion junction in mechanisms action hypolipidemic (HLT) and antithrombotic (ATT) therapy and some reviews on this topic are discussed. Difficalties in distinguishing coexistent of HLT and ATT effects are in their multilevel nature: intercellular interaction with receptors, transmembrane transport, intracellular coaction, role of immune mechnisms and so on. Experimental studies revealed retardation of arherosclerosis in coronary arteries. Modern methods of visualization technic givies us the possibility to study dynamics of atherosclerotic disease of men in vivo