Variability of lipid spectrum indicators for people of different genders and ages with acute and chronic disorders cerebral circulation

Abstract

The purpose of the study: to compare the lipid spectrum indicators in the acute period of cerebral stroke and in chronic brain ischemia in patients of different gender and age, and to determine the value of these indicators for the formation of stroke and its clinical outcomes.
Material and methods. 125 patients of different gender and age were examined: 74 in the acute period of cerebral stroke, 51 in chronic brain ischemia. The levels of total cholesterol, low-and high-density lipoproteins, and triglycerides were determined, and the atherogenicity coefficient was calculated. The comparison of lipid spectrum indicators with the severity of post-stroke functional defect was performed.
Results and conclusion. A clear relationship between the level of high-density lipoproteins and triglycerides with gender and age characteristics and the nature of cerebrovascular pathology was determined. The pathological profile of lipids is more important for the formation of chronic brain ischemia than as a risk factor for stroke in both sexes. The degree of recovery of functions impaired as a result of stroke is positively correlated with some increase in total cholesterol and triglycerides, especially in older men. This can be explained by considering these lipids as a source of energy, compensatory potential, which plays a positive role in the recovery process