Взаимосвязь структуры  и секреторной функции жировой  ткани с развитием атеросклероза  по данным позитронно-эмиссионной  томографии. Обзор литературы

M. E. Bugriy; I. V. Sergienko; V. B. Sergienko

doi:10.34687/2219-8202.JAD.2020.04.0002

Authors

M. E. Bugriy National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation
I. V. Sergienko National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation
V. B. Sergienko National Medical Research Center of Cardiology of the Ministry of healthcare of the Russian Federation

DOI:

https://doi.org/10.34687/2219-8202.JAD.2020.04.0002

Keywords:

atherosclerosis, adipose tissue, adiponectin, brown adipose tissue, Dual-energy X-ray absorptiometry, positron-emission tomography, 18F-FDG, 18F-sodium fluoride, 68Ga

Abstract

Endocrine function impairment with adipokine disbalance and decreasing adiponectin production is key point of atherosclerosis development with endothelial inflammation and dysfunction. Precise estimation of adipose tissue and brown fat by Dual-energy X-ray absorptiometry and FDG PET/CT with pharmacological stimulation by β3-adrenoceptor agonist allow more accurately characterize degree of adipokine imbalance and be independent atherosclerosis risk factor. Positron emission tomography is one of most sensitive and accurate methods for atherosclerosis plaque assessment with some radiopharmaceuticals, include 18F-FDG, 18F-sodium fluoride and 68Ga radiopharmaceuticals.