Lipid metabolism seasonal variability in men under 60 years old (living in Saint-Petersburg, Russia) within initial period of myocardial infarction

Abstract

Aim. Evaluation of lipid metabolism variations during different year seasons in men under 60 years old within acute and subacute phases of myocardial infarction (MI) to assess their significance for prevention.
Material and methods. For the period of 2000–2015 the lipid profile investigation was conducted in 566 men with MI under 60 y.o. at the first 48 hours and at the end of the third week from the disease onset in relation to the climatic seasonal average daily air temperature of St. Petersburg, Russia.
Results. Reliable evidences of lipid level characteristics changes depending on the seasonal variances have been identified with peak atherogenic changes in winter and spring and low-density lipoprotein levels in summer. The unfavorable dynamics of cholesterol and triglycerides concentration during a treatment course were detected in winter and in summer.

Conclusions. The obtained data justify the necessity to use the seasonal periodicity of average daily air temperature changes for the correction of dyslipidemia within the implementation of preventive programs framework.