Разработка калькулятора для  лабораторной диагностики риска  развития коронарного атеросклероза

E. V. Kashtanova; Ya. V. Polonskaya; I. N. Yakovina; N. A. Bannova; Yu. I. Ragino

Development of a calculator for laboratory diagnosis of the risk assessment of coronary atherosclerosis

Authors

E. V. Kashtanova Scientific Institution of Internal and Preventive Medicine, Novosibirsk state technical University
Ya. V. Polonskaya Scientific Institution of Internal and Preventive Medicine
I. N. Yakovina Novosibirsk state technical University
N. A. Bannova Novosibirsk state technical University
Yu. I. Ragino Scientific Institution of Internal and Preventive Medicine

Keywords:

coronary heart disease, risk, coronary atherosclerosis, laboratory diagnosis

Abstract

The aim of this study was to develop a calculator for the laboratory diagnostics of risk of development of
coronary atherosclerosis and ischemic heart disease including relevant biochemical parameters, characterizing the basic pathogenetic links of coronary atherosclerosis.
Materials and methods. The study included 288 men with coronary heart disease (200 diagnosis of coronary artery disease was verified by coronary angiography data) and 312 men without coronary artery disease. All patients were determined biochemical parameters. Risk assessment of coronary atherosclerosis was performed using the logical-mathematical method. Results. The basis of the logical-mathematical model is based on the previously developed laboratory-diagnostic complex, which included the following parameters: initial level of POL products in LDL, LDL resistance to oxidation, blood concentration of basal insulin, hsCRP, аpоА1 and apoВ, TG and HDL-cholesterol. For the resulting generalized model performed its testing on real data and assessment, involving the calculation of the characteristics of diagnostic accuracy, specificity and sensitivity.
Conclusion. This model represents a generic pattern processing laboratory parameters, which takes i

Downloads

Download data is not yet available.

Downloads

PDF (Русский)

Published

2017-12-20

How to Cite

Kashtanova E. V., Polonskaya Y. V., Yakovina I. N., Bannova N. A., Ragino Y. I. Development of a calculator for laboratory diagnosis of the risk assessment of coronary atherosclerosis // The Journal of Atherosclerosis and Dyslipidemias. 2017. VOL. № 4 (29). PP. 62–68.

MLA
GOST

Download Citation

Issue

No. 4 (29) (2017)

Section

Original research paper

Most read articles by the same author(s)

V. V. Kukharchuk, M. V. Ezhov, I. V. Sergienko, G. G. Arabidze, M. G. Bubnova, T. V. Balakhonova, V. S. Gurevich, M. A. Kachkovsky, G. A. Konovalov, V. O. Konstantinov, P. P. Malyshev , S. D. Pokrovsky, A. A. Sokolov, A. B. Sumarokov, N. B. Gornyakova, A. G. Obrezan, I. I. Shaposhnik, M. B. Antsiferov, A. A. Ansheles, D. M. Aronov, N. M. Akhmedzhanov, O. L. Barbarash , S. A. Boitsov, M. I. Voivoda, G. R. Galstyan, A. S. Galyavich, O. M. Drapkina, D. V. Duplyakov, S. Ya. Eregin, R. S. Karpov, Yu. A. Karpov, N. A. Koziolova, E. D. Kosmachev, D. V. Nebieridze, S. V. Nedogoda, V. E. Oleynikov, Yu. I. Ragino, V. V. Skibitsky, O. G. Smolenskaya, A. E. Filippov, Yu. Sh. Halimov, I. E. Chazova, M. V. Shestakova, S. S. Yakushin, Diagnostics and correction of lipid metabolism disorders in order to prevent and treat of atherosclerosis Russian recommendations VII revision. Moscow, 2020 , The Journal of Atherosclerosis and Dyslipidemias: No. 1 (38) (2020)
U. V. Chubykina, M. V. Ezhov, T. A. Rozhkova , B. M. Tamaeva, A. A. Sokolov, A. I. Ershova, A. N Meshkov, V. I. Mikhailina, A. V. Blokhina, A. S. Limonova, O. V. Kopylova, I. I. Shaposhnik, V. V. Genkel , V. S. Gurevich, S. A. Urazgildeeva, A. V. Tregubov, M. V. Muzalevskaya, M. I. Voevoda, O. V. Timoshchenko, E. V. Shakhtshneider, Yu. I. Ragino, I. V. Leontyeva, L. V. Egorov, I. N. Zakharova, I.I. Pshenichnikova, D. I. Sadykova, E. S. Slastnikova, L. F. Galimova, E. D. Kosmacheva, A. M. Namitokov, A. S. Alieva, A. S. Galyavich, Z. F. Kim, V. A. Korneva, T. Yu. Kuznetsova, A. E. Filippov, A. M. Tuktarov, A. S. Vorobyov, I. D. Astrakhantseva, D. Yu. Bogdanov, M. A. Kachkovsky, A. V. Egorova, V. O. Konstantinov, M. P. Serebrenitskaya, V. K. Zafiraki, N. N. Bizyaeva, N. G. Androsyuk, M. A. Kiseleva, Yu. G. Grigorieva, O.Yu. Korennova, Yu. E. Yukhina, M. D. Devyatova, O. N. Ivanova, P. A. Vasiliev, I. V. Avdeeva, V. E. Oleinikov, Yu. A. Vorobieva, Yu. A. Ermakova, N. V. Mukha, D. N. Zaitsev, M. V. Zykov, A.V. Isaeva, T. I. Petelina, E. V. Mikova, A five-year follow-up period in homo- and heterozygous familial hypercholesterolemia patients of the RENAISSANCE registry , The Journal of Atherosclerosis and Dyslipidemias: No. 1(50) (2023)
M. V. Ezhov, I. V. Sergienko, D. M. Aronov, G. G. Arabidze, N. M. Akhmedzhanov, S. S. Bazhan, T. V. Balakhonova, O. L. Barbarash, S. A. Boytsov, M. G. Бубнова Bubnova, M. I. Voevoda, A. S. Galyavich, N. B. Gornyakova, V. S. Gurevich, O. M. Drapkina, D. V. Duplyakov, S. Ya. Yeregin, M. Yu. Zubareva, R.S. Karpov, Yu. A. Karpov, N. A. Koziolova, G. A. Konovalov, V. O. Konstantinov, E. D. Kosmacheva, A. I. Martynov, D. V. Nebieridze, S. N. Pokrovsky, Yu. I. Ragino, V. V. Skibitsky, O. G. Smolenskaya, I. E. Chazova, S. A. Shalnova, I. I. Shaposhnik, V. V. Kukharchuk , Diagnostics and correction of lipid metabolism disorders in order to prevent and treat atherosclerosis. Russian recommendations VI revision , The Journal of Atherosclerosis and Dyslipidemias: No. 3 (28) (2017)
A. V. Anikina, M. E. Amelin, L. V. Shcherbakova, Yu. I. Ragino, Clinical and biochemical parameters associated with changes in the structure of the achilles tendon in men with atherosclerosis , The Journal of Atherosclerosis and Dyslipidemias: No. 1(50) (2023)
Ia. V. Polonskaya, V. S. Shramko, S. V. Morozov, E. I. Chernyak, A. M. Chernyavsky, Yu. I. Ragino, Spectrum of fatty acids, lipids and markers of inflammation in patients with coronary atherosclerosis , The Journal of Atherosclerosis and Dyslipidemias: No. 1 (30) (2018)
M. V. Ezhov, I. V. Sergienko, D. V. Duplyakov, O. E. Abashina, M. A. Kachkovsky, I. I. Shaposhnik, V. V. Genkel, V. S. Gurevich, S. A. Urazgildeeva, A. V. Tregubov, T. V. Konovalova, M. V. Muzalevskaya, M. I. Voevoda, S. S. Bazhan, K. V. Makarenkova, O. V. Timoshenko, Yu. I. Ragino, I. A. Urvantseva, K. G. Cozhocar, A. A. Sokolov, O. I. Boeva, E. V. Bolotova, Yu. B. Kushnaryova, T. Yu. Kuznetsova, V. A. Korneva, D. Yu. Bogdanov, E. E. Chichina, V. M. Soloviev, O. G. Smolenskaya, A. S. Galyavich, M. S. Safarova, A. V. Popova, V. V. Malakhov, A. A. Ansheles, D. N. Nozadze, A. E. Semenova, T. A. Rozhkova, E. Yu. Solov’eva, N. B. Gornyakova, Yu. A. Karpov, V. V. Kukharchuk, Results of the Russian research program on the diagnosis and treatment of patients with familial hypercholesterolemia. High prevalence, low awareness, poor adherence , The Journal of Atherosclerosis and Dyslipidemias: No. 2 (27) (2017)
A. V. Anikina, L. V. Shcherbakova, Mikhail E. Amelin, Yu. I. Ragino, The study of X-ray morphological features of the Achilles tendon in men with atherosclerosis of various localization. , The Journal of Atherosclerosis and Dyslipidemias: No. 4 (49) (2022)
K. S. Benimetskaya, K. V. Makarenkova, L. D. Latyntseva, O. V. Tsygankova, S. V. Astrakov, E. V. Shachtschneider, Yu. I. Ragino, M. I. Voivode, Evolocumab had no effect in young women with familial hypercholesterolemia , The Journal of Atherosclerosis and Dyslipidemias: No. 1 (30) (2018)
V. S. Shramko, L. V. Shcherbakova, G. I. Simonova, A. D. Khudyakova, Yu. A. Balanova, A. E. Imaeva, S. A. Shalnova, Yu. I. Ragino, Study of associations of blood fatty acid spectrum with lipid profile in men of Novosibirsk (ESSE-RF3 in the Novosibirsk region) , The Journal of Atherosclerosis and Dyslipidemias: No. 1(54) (2024)
N. I. Tkacheva, S. B. Morozov, E. M. Stakhneva, V. S. Shramko, Yu. I. Ragino, Chromatographic determination of the content of fatty acids in different biological environments at atherosclerotic damages , The Journal of Atherosclerosis and Dyslipidemias: No. 1 (26) (2017)

1 2 > >>

Development of a calculator for laboratory diagnosis of the risk assessment of coronary atherosclerosis

Authors

Keywords:

Abstract

Downloads

Downloads

Published

How to Cite

Issue

Section

Most read articles by the same author(s)

Language

Make a Submission

Information

Indexing

Editor-in-chief

Rating

Current Issue