Management of Dyslipidemia for chronic forms of coronary artery disease: a review of Guidelines

Abstract

Aim. The article provides an overview of Guidelines for the мanagement of dyslipidaemias (USА, UK and the European Society of Cardiology) in patients with documented coronary heart disease (CHD). The article compares the target criteria of lipid-lowering therapy; indication for use of statins, еzetimibe, bile acid sequestrants, fibrates, PCSK9 inhibitors, drug combinations. Are considered indications for therapies used in special situations; drugs recommended in some guidelines and missing in others. All of Guidelines the preparation of the first row are the statins, in case of intolerance or failure to achieve the target level of low density lipoprotein cholesterol – ezetimibe. The role and place of other drugs (against the background of insufficient evidence on the impact of adverse cardiovascular events) in different recommendations.