An abdominal aortic calcification in peripheral arterial occlusive disease: risk factors and markers

Authors

  • M. Melnikov North-Western State Medical University named after I.I. Mechnikov
  • V. Zelinskiy North-Western State Medical University named after I.I. Mechnikov
  • S. Zhorin North-Western State Medical University named after I.I. Mechnikov
  • D. Chuglova North-Western State Medical University named after I.I. Mechnikov

Keywords:

calcinosis, abdominal aorta, peripheral arterial occlusive disease, atherosclerosis, risk factor, marker

Abstract

Purpose. The objective of the study was to determine the strength predictors and markers of an abdominal aortic calcification in patients with peripheral arterial occlusive disease.
Materials and methods. A total of 193 patients with peripheral arterial occlusive disease were included in the study. The study group included 108 patients with objective sign of an abdominal aortic calcification. The control group was presented by 85 patients with peripheral arterial occlusive disease without an abdominal aortic calcification. An abdominal aortic calcification have been verified by CT-imaging. Multivariate logistic regression identified predictors and markers of an abdominal aortic calcification. Odd ratios were adjusted for patient demographics, comorbidities and laboratory values.
Results. Multivariate predictors and markers of an abdominal aortic calcification included female gender, systolic arterial hypertension, smoking duration, hyperhomocysteinemia, a high serum C-reactive protein level, ischemic heart disease, cerebrovascular disease and osteoporosis.
Conclusion. Identification of an abdominal aortic calcification predictors and markers might significantly influence the treatment strategy, short and long-term outcomes in patients with peripheral arterial occlusive disease follow vascular interventions.

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Published

2014-09-26

How to Cite

Melnikov M., Zelinskiy V., Zhorin S., Chuglova D. An abdominal aortic calcification in peripheral arterial occlusive disease: risk factors and markers // The Journal of Atherosclerosis and Dyslipidemias. 2014. VOL. № 3 (16). PP. 33–38.

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Original research paper