Abdominal aortic calcification in peripheral arterial occlusive disease: risk factors and markers

Abstract

Aim. The objective of the study was to determine the most significant predictors and markers of an abdominal aortic calcification in patients with peripheral arterial occlusive disease.
Methods. A total of 193 patients with peripheral arterial occlusive disease were included in the study. The study group included 108 patients with objective signs of an abdominal aortic calcification. The control group was presented by 85 patients with peripheral arterial occlusive disease without an abdominal aortic calcification. An abdominal aortic calcification have been verified by CT-imaging. Multivariate logistic regression analysis identified predictors and markers of an abdominal aortic calcification. Odd ratios were adjusted for demographics, comorbidities and laboratory values of patients.
Results. Multivariate predictors and markers of abdominal aortic calcification included female gender, systolic arterial
hypertension, smoking duration, hyperhomocysteinemia, elevated serum C-reactive protein levels, ischemic heart disease, cerebrovascular disease and osteoporosis.
Conclusion. Identification of abdominal aortic calcification predictors and markers may significant influence on the treatment strategy, short and long-term outcomes in patients with peripheral arterial occlusive disease.